HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Nitrobenzaldehyde → HCID 53866353, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Nitrobenzaldehyde | HCID 7449 | — |
| Reactant | Propan-2-yl 3-amino-3-ethoxyprop-2-enoate | HCID 71366472 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 53866353 | HCID 53866353 | 45% |
Reaction Steps
Heating a solution of 6.1 g of 3-nitrobenzaldehyde and 13.9 g of 3-amino-3-ethoxyacrylic acid isopropyl ester in 100 ml of ethanol for 8 hours yields 2-amino-6-ethoxy-4-(3-nitrophenyl)-4,5-dihydropyridine-3,5-dicarboxylic acid diisopropyl ester of melting point 130° C (ether/petroleum ether). Yield: 45% of theory.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03985886 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-4b8fa981b307440b93ead627b3314265 |
| Source note | uspto-grants-1976_10 |