HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 2-(2-Bromo-4,5-dimethoxyphenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-Bromo-N-(1-hydroxy-2-methylpropan-2-yl)-4,5-dimethoxybenzamide | HCID 12319365 | — |
| Product | 2-(2-Bromo-4,5-dimethoxyphenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole | HCID 12319367 | — |
Reaction Steps
Reaction of 2-bromo-4,5-dimethoxy-N-(1-hydroxy-2-methyl-2-propyl)benzamide and thionyl chloride by the method described in Example 1b provides 2-(2-bromo-4,5-dimethoxyphenyl)-4,4-dimethyl-2-oxazoline as colorless crystals, m.p. 49°-51°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03985889 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-b586e154ad8646b290d3b794ad9c1638 |
| Source note | uspto-grants-1976_10 |