1-Methyl-4-piperidone → HCID 21506839, compound

HRID 1287902Notes

Reaction equation

Br[C:2]1[CH:7]=[C:6]2[O:8][CH2:9][O:10][C:5]2=[CH:4][C:3]=1[C:11]1[O:12][CH2:13][C:14]([CH3:17])([CH3:16])[N:15]=1.[CH3:18][N:19]1[CH2:24][CH2:23][C:22](=[O:25])[CH2:21][CH2:20]1>>[CH3:16][C:14]1([CH3:17])[CH2:13][O:12][C:11]([C:3]2[CH:4]=[C:5]3[O:10][CH2:9][O:8][C:6]3=[CH:7][C:2]=2[C:22]2([OH:25])[CH2:23][CH2:24][N:19]([CH3:18])[CH2:20][CH2:21]2)=[N:15]1

Participants

Reactant 2

HCID 740491-Methyl-4-piperidone

HCID 372294NSC647353

Product 1

HCID 21506839HCID 21506839, compound

Procedure

Reaction of 2-(2-bromo-4,5-methylenedioxyphenyl)-4,4-dimethyl-2-oxazoline and 1-methyl-4-piperidone by the method described in Example 1c provides 4-[2 -(4,4-dimethyl-2-oxazolin-2-yl)-4,5-methylenedioxyphenyl]-4-hydroxy-1-methylpiperidine.

Sources & evidence

ORD record: ord-51a9118fd1f541a896700db1de412152
Source dataset: uspto-grants-1976_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03985889

Reaction notes

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