HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 21506820, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1-(Cyclopropylmethyl)-4-[2-(hydroxymethyl)phenyl]piperidin-4-ol | HCID 53969435 | — |
| Product | HCID 21506820 | HCID 21506820 | — |
Reaction Steps
Treatment of 1-cyclopropylmethyl-4-hydroxy-4-(α-hydroxy-2-tolyl)piperidine with hydrochloric acid by the method described in Example 16d provides 1'-cyclopropylmethyl-1,3-dihydrospiro[isobenzofuran-1,4'-piperidine] as an oil (hydrochloride salt, m.p. 222°-224°).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03985889 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-cbeae92f6e8246258510392eead78ec0 |
| Source note | uspto-grants-1976_10 |