HCID 53858121, compound → HCID 10036300, compound

HRID 1287910Notes

Reaction equation

HRID 1287910 reaction equation
[CH2:1]([N:3]1[CH2:8][CH2:7][C:6]([OH:17])([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=2[CH2:15]O)[CH2:5][CH2:4]1)[CH3:2]>C(O)=O>[CH2:1]([N:3]1[CH2:4][CH2:5][C:6]2([C:9]3[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=3)[CH2:15][O:17]2)[CH2:7][CH2:8]1)[CH3:2]

Participants

3

Reactant 1

HCID 53858121HCID 53858121, compound

Product 1

HCID 10036300HCID 10036300, compound

Reagents, catalysts & solvents 1

HCID 284Formic AcidSolvent

Procedure

Treatment of 1-ethyl-4-hydroxy-4-(α-hydroxy2-tolyl)piperidine with formic acid by the method described in Example 17c provides 1,3-dihydro-1'-ethylspiro[isobenzofuran-1,4'-piperidine] as an oil.

Sources & evidence

ORD record
ord-b2084ff0d750496fabe7eaac0dae790f
Source dataset
uspto-grants-1976_10
Patent number
US03985889

Reaction notes

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