1-Methyl-4-piperidone → HCID 86733527, compound

HRID 1287912Notes

Reaction equation

HRID 1287912 reaction equation
Br[C:2]1[CH:9]=[CH:8][C:7]([CH3:10])=[CH:6][C:3]=1[CH2:4][OH:5].[CH3:11][N:12]1[CH2:17][CH2:16][C:15](=[O:18])[CH2:14][CH2:13]1>>[OH:18][C:15]1([C:2]2[CH:9]=[CH:8][C:7]([CH3:10])=[CH:6][C:3]=2[CH2:4][OH:5])[CH2:16][CH2:17][N:12]([CH3:11])[CH2:13][CH2:14]1

Participants

3

Reactant 2

HCID 740491-Methyl-4-piperidoneHCID 54173415(2-Bromo-5-methylphenyl)methanol

Product 1

HCID 86733527HCID 86733527, compound

Procedure

Reaction of 2-bromo-5-methylbenzyl alcohol and 1-methyl-4-piperidone by the method described in Example 16a provides 4-hydroxy-4-(α-hydroxy-5-methyl-2-tolyl)-1-methylpiperidine.

Sources & evidence

ORD record
ord-ae6e9518eec8439fa6113f16766dccdd
Source dataset
uspto-grants-1976_10
Patent number
US03985889

Reaction notes

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