Pyridinium chloride → 1-[2-(4-Hydroxynaphthalen-1-yl)-1-benzofuran-3-yl]ethan-1-one

Participants

Reaction Steps

A mixture of 13.8 g. (0.044 mol.) of 3-acetyl-2-(4-methoxynaphthyl)benzofuran and 100 g. of pyridine hydrochloride was heated at 185° for 4.5 hours. The hot reaction mixture was poured into an ice-dilute hydrochloric acid mixture and the aqueous solution was extracted with ether. The extract was dried (MgSO4) and evaporated to give 3-acetyl-2-(4-hydroxynaphthyl)benzofuran, m.p. 212°-216°.

Provenance & Evidence