Ammonia → HCID 21503112, compound

HRID 1287945Notes

Reaction equation

HRID 1287945 reaction equation
[CH2:1]([O:8][CH2:9][C:10]1([CH3:21])[CH2:14][O:13][C:12]([CH3:20])([C:15](OCC)=[O:16])[O:11]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH3:22]>>[CH2:1]([O:8][CH2:9][C:10]1([CH3:21])[CH2:14][O:13][C:12]([CH3:20])([C:15]([NH2:22])=[O:16])[O:11]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 222AmmoniaHCID 21503115HCID 21503115, compound

Product 1

HCID 21503112HCID 21503112, compound

Procedure

Ethyl 4-benzyloxymethyl-2,4-dimethyl-1,3-dioxolan-2-carboxylate (5.0 grams) and concentrated aqueous ammonia solution (50 milliliters, 0.880 S.G.) were stirred together at room temperature for 3 days. The white solid formed was filtered off, washed with water and recrystallised from cyclohexane to give the desired product as an isomer mixture melting point 72°-92° C.

Workup

  1. customThe white solid formed
  2. filtrationwas filtered off
  3. washwashed with water
  4. customrecrystallised from cyclohexane

Sources & evidence

ORD record
ord-07ef5be95fca44418016bd6ccd0bb31e
Source dataset
uspto-grants-1976_10
Patent number
US03986860

Reaction notes

Loading…