HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 4-acetoxy-3,5-Bis(1-methylethyl)benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 4-Hydroxy-3,5-bis(isopropyl)benzaldehyde | HCID 82712 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | 4-acetoxy-3,5-Bis(1-methylethyl)benzaldehyde | HCID 19375072 | — |
Reaction Steps
3,5-bis(1-methylethyl)-4-hydroxybenzaldehyde is acetylated with acetic anhydride in refluxing 1,2-dichloroethane, in the presence of DMAP, to provide 4-acetoxy-3,5-Bis(1-methylethyl)benzaldehyde. This material is converted by the method of example 2 into the title compound, obtained as a white solid, mp 95°-97° after recrystallization from hexane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05464865 |
| Source dataset | uspto-grants-1995_11 |
| ORD ID | ord-e473a5f3f5384d65b69756244cd94348 |
| Source note | uspto-grants-1995_11 |