HCID 53759317, compound → HCID 12197399, compound

HRID 1288024Notes

Reaction equation

HRID 1288024 reaction equation
[CH3:1][N:2]1[C:6]([CH:7]=[N:8][NH:9][C:10]([NH2:12])=[S:11])=[CH:5][N:4]=[C:3]1[N+:13]([O-:15])=[O:14]>O>[NH2:12][C:10]1[S:11][C:7]([C:6]2[N:2]([CH3:1])[C:3]([N+:13]([O-:15])=[O:14])=[N:4][CH:5]=2)=[N:8][N:9]=1

Participants

3

Reactant 1

HCID 53759317HCID 53759317, compound

Product 1

HCID 12197399HCID 12197399, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

2 Grams of 1-methyl-2-nitro-5-imidazolecarboxaldehyde thiosemicarbazone are added to a solution of 17.1 g. of FeNH4 (SO4)2. 12H2O in 35 ml. of water. The mixture is stirred at 80°-90° C. for 2 hours, and, after cooling, the solid product is collected on the filter and washed with water. The crude compound is crystallized from a mixture of methanol and dimethylformamide. Yield 0.95 g. (48%), m.p. 263°-265° C.

Workup

  1. temperatureafter cooling
  2. customthe solid product is collected on the
  3. filtrationfilter
  4. washwashed with water
  5. customThe crude compound is crystallized from a mixture of methanol and dimethylformamide

Sources & evidence

ORD record
ord-bb27abf1febd427dbdd47ddfc19f58ea
Source dataset
uspto-grants-1976_10
Patent number
US03987053

Reaction notes

Loading…