反应详情

To a solution of 0.15 g. of 1-methyl-2-nitro-5-hydroxymethylimidazole in 20 ml. of benzene, 0.33 g. of MnO2 is added and the reaction mixture is heated on the steambath for two hours. After filtration and evaporation to dryness under vacuum, the crude product is crystallized from ethyl acetate and 0.060 g. (40.5%) of 1-methyl-2-nitro-5-imidazolaldehyde is obtained.

1. temperaturethe reaction mixture is heated on the steambath for two hours
2. filtrationAfter filtration and evaporation to dryness under vacuum
3. customthe crude product is crystallized from ethyl acetate and 0.060 g