Benzeneacetic acid, hydrazide → HCID 21489332, compound

HRID 1288062Notes

Reaction equation

HRID 1288062 reaction equation
[CH2:1]([C:3]1[C:8]2[C:9]([C:15]3[CH:20]=[CH:19][CH:18]=[C:17]([CH2:21][CH3:22])[CH:16]=3)=[N:10][CH2:11][C:12](=S)[NH:13][C:7]=2[CH:6]=[C:5]([CH2:23][CH3:24])[CH:4]=1)[CH3:2].[C:25]1([CH2:31][C:32]([NH:34][NH2:35])=O)[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>C(O)C>[CH2:1]([C:3]1[C:8]2[C:9]([C:15]3[CH:20]=[CH:19][CH:18]=[C:17]([CH2:21][CH3:22])[CH:16]=3)=[N:10][CH2:11][C:12]3[N:13]([C:32]([CH2:31][C:25]4[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=4)=[N:34][N:35]=3)[C:7]=2[CH:6]=[C:5]([CH2:23][CH3:24])[CH:4]=1)[CH3:2]

Participants

4

Reactant 2

HCID 70301Benzeneacetic acid, hydrazideHCID 19865767HCID 19865767, compound

Product 1

HCID 21489332HCID 21489332, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
250 °C

Procedure

In the manner given in Example 2, 6,8-diethyl-1,3-dihydro-5-(m-ethylphenyl)-2H-1,4-benzodiazepine-2-thione is heated in ethanol with phenylacetic acid hydrazide and the resulting product heated to 250° C. to give 7,9-diethyl-1-benzyl-6-(m-ethylphenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine.

Sources & evidence

ORD record
ord-31f8c6dc1d3b49faa13c45392a8396d9
Source dataset
uspto-grants-1976_10
Patent number
US03987052

Reaction notes

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