Phenyl chloroformate → HCID 54193432, compound

HRID 1288115Notes

Reaction equation

C([N:8]1[CH2:22][CH2:21][C:20]2[C:11](=[N:12][C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][C:18]=3[C:19]=2[CH3:23])[CH2:10][CH2:9]1)C1C=CC=CC=1.Cl[C:25]([O:27][C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1)=[O:26]>>[C:28]1([O:27][C:25]([N:8]2[CH2:22][CH2:21][C:20]3[C:11](=[N:12][C:13]4[CH:14]=[CH:15][CH:16]=[CH:17][C:18]=4[C:19]=3[CH3:23])[CH2:10][CH2:9]2)=[O:26])[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1

Participants

Reactant 2

HCID 15891Phenyl chloroformate

HCID 21503431HCID 21503431, compound

Product 1

HCID 54193432HCID 54193432, compoundYield 63%

Procedure

1,2,4,5-Tetrahydro-11-methyl-3-azepino[4,5-b]quinoline-carboxylic acid phenyl ester was prepared from 3-benzyl-1,2,4,5-tetrahydro-11-methyl- 3H-azepino[4,5-b]quinoline and phenyl chloroformate analogous to Example 59.

Sources & evidence

ORD record: ord-3280402bea1844a4a1f2d11928cfdb82
Source dataset: uspto-grants-1976_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03987047

Reaction notes

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