Ethyl chloroformate → HCID 68139179, compound

HRID 1288120Notes

Reaction equation

[CH2:1]([C:4]1[C:13]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2[N:7]=[C:6]2[CH2:14][CH2:15][NH:16][CH2:17][CH2:18][C:5]=12)[CH2:2][CH3:3].[Cl:19][C:20]([O:22][CH2:23][CH3:24])=[O:21]>>[ClH:19].[CH2:23]([O:22][C:20]([N:16]1[CH2:17][CH2:18][C:5]2[C:6](=[N:7][C:8]3[CH:9]=[CH:10][CH:11]=[CH:12][C:13]=3[C:4]=2[CH2:1][CH2:2][CH3:3])[CH2:14][CH2:15]1)=[O:21])[CH3:24]

Participants

Reactant 2

HCID 10928Ethyl chloroformate

HCID 3044003HCID 3044003, compound

Product 1

HCID 68139179HCID 68139179, compoundYield 84%

Procedure

1,2,4,5-Tetrahydro-11-propyl-3-azepino[4,5-b]quinoline-carboxylic acid ethyl ester hydrochloride was prepared from 1,2,4,5-tetrahydro-11-propyl-3H-azepino[4,5-b]quinoline and ethyl chloroformate analogous to Example 63.

Sources & evidence

ORD record: ord-1cf13c288bb14e9abedf83329632ee11
Source dataset: uspto-grants-1976_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03987047

Reaction notes

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