Ethyl chloroformate → HCID 68140346, compound

HRID 1288128Notes

Reaction equation

[CH3:1][C:2]1[C:11]2[CH:10]=[C:9]([N+:12]([O-:14])=[O:13])[CH:8]=[CH:7][C:6]=2[N:5]=[C:4]2[CH2:15][CH2:16][NH:17][CH2:18][CH2:19][C:3]=12.[Cl:20][C:21]([O:23][CH2:24][CH3:25])=[O:22]>>[ClH:20].[CH2:24]([O:23][C:21]([N:17]1[CH2:18][CH2:19][C:3]2[C:4](=[N:5][C:6]3[CH:7]=[CH:8][C:9]([N+:12]([O-:14])=[O:13])=[CH:10][C:11]=3[C:2]=2[CH3:1])[CH2:15][CH2:16]1)=[O:22])[CH3:25]

Participants

Reactant 2

HCID 10928Ethyl chloroformate

HCID 215035402,3,4,5-Tetrahydro-11-methyl-9-nitro-1H-azepino[4,5-b]quinoline

Product 1

HCID 68140346HCID 68140346, compoundYield 51%

Procedure

1,2,4,5-Tetrahydro-11-methyl-9-nitro-3-azepino[4,5-b]quinoline-carboxylic acid ethyl ester hydrochloride was prepared from 1,2,4,5-tetrahydro-11-methyl-9-nitro-3H-azepino[4,5-b]quinoline and ethyl chloroformate analogous to Example 63.

Sources & evidence

ORD record: ord-3f538801877f40e690f1cf1a07c80e33
Source dataset: uspto-grants-1976_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03987047

Reaction notes

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