Ethyl chloroformate → HCID 68139462, compound

HRID 1288131Notes

Reaction equation

[CH3:1][CH:2]1[C:8]2=[N:9][C:10]3[CH:11]=[CH:12][CH:13]=[CH:14][C:15]=3[C:16]([CH3:17])=[C:7]2[CH2:6][CH2:5][NH:4][CH2:3]1.[Cl:18][C:19]([O:21][CH2:22][CH3:23])=[O:20]>>[ClH:18].[CH2:22]([O:21][C:19]([N:4]1[CH2:5][CH2:6][C:7]2[C:8](=[N:9][C:10]3[CH:11]=[CH:12][CH:13]=[CH:14][C:15]=3[C:16]=2[CH3:17])[CH:2]([CH3:1])[CH2:3]1)=[O:20])[CH3:23]

Participants

Reactant 2

HCID 10928Ethyl chloroformate

HCID 21503574HCID 21503574, compound

Product 1

HCID 68139462HCID 68139462, compoundYield 84%

Procedure

1,2,4,5-Tetrahydro-5,11-dimethyl-3-azepino[4,5-b]quinoline-carboxylic acid ethyl ester hydrochloride was prepared from 1,2,4,5-tetrahydro-5,11-dimethyl-3H-azepino[4,5-b]quinoline and ethyl chloroformate analogous to Example 63.

Sources & evidence

ORD record: ord-4a0d2e231634497ca8e765c8745f5032
Source dataset: uspto-grants-1976_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03987047

Reaction notes

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