Ethyl chloroformate → HCID 53840016, compound

HRID 1288137Notes

Reaction equation

[OH:1][CH:2]1[C:8]2=[N:9][C:10]3[CH:11]=[CH:12][CH:13]=[CH:14][C:15]=3[CH:16]=[C:7]2[CH2:6][NH:5][CH2:4][CH2:3]1.Cl[C:18]([O:20][CH2:21][CH3:22])=[O:19]>>[CH2:21]([O:20][C:18]([N:5]1[CH2:4][CH2:3][CH:2]([O:1][C:18]([O:20][CH2:21][CH3:22])=[O:19])[C:8]2=[N:9][C:10]3[CH:11]=[CH:12][CH:13]=[CH:14][C:15]=3[CH:16]=[C:7]2[CH2:6]1)=[O:19])[CH3:22]

Participants

Reactant 2

HCID 10928Ethyl chloroformate

HCID 21503503HCID 21503503, compound

Product 1

HCID 53840016HCID 53840016, compoundYield 80%

Procedure

5-(Ethoxy-carbonyloxy)-2,3,4,5-tetrahydro-1H-2-azepino [4,3-b]quinoline-carboxylic acid ethyl ester was prepared from 5-hydroxy-2,3,4,5-tetrahydro-1H-azepino[4,3-b]quinoline and ethyl chloroformate analogous to Example 63.

Sources & evidence

ORD record: ord-1c2c2ade76be49999ab9cdd7c5fae54e
Source dataset: uspto-grants-1976_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03987047

Reaction notes

Loading…