Ethyl chloroformate → HCID 178473316, compound

HRID 1288142Notes

Reaction equation

HRID 1288142 reaction equation
C([N:8]1[CH2:22][CH2:21][C:20]2[C:11](=[N:12][C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][C:18]=3[C:19]=2[OH:23])[CH2:10][CH2:9]1)C1C=CC=CC=1.Cl[C:25]([O:27][CH2:28][CH3:29])=[O:26]>>[CH2:28]([O:27][C:25]([N:8]1[CH2:22][CH2:21][C:20]2[C:11](=[N:12][C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][C:18]=3[C:19]=2[OH:23])[CH2:10][CH2:9]1)=[O:26])[CH3:29]

Participants

3

Reactant 2

HCID 10928Ethyl chloroformateHCID 178515157HCID 178515157, compound

Product 1

HCID 178473316HCID 178473316, compoundYield 20%

Procedure

11-Hydroxy-1,2,4,5-tetrahydro-3-azepino[4,5-b]quinoline-carboxylic acid ethyl ester was prepared analogous to Example 101 from 3-benzyl-11-hydroxy-1,2,4,5-tetrahydro-3H-azepino[4,5-b]quinoline and ethyl chloroformate.

Sources & evidence

ORD record
ord-2bf04f28cc004779845346a9be9de804
Source dataset
uspto-grants-1976_10
Patent number
US03987047

Reaction notes

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