Acetyl chloride → HCID 21503670, compound

HRID 1288144Notes

Reaction equation

HRID 1288144 reaction equation
[CH3:1][C:2]1[C:11]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[N:5]=[C:4]2[CH2:12][CH2:13][NH:14][CH2:15][CH2:16][C:3]=12.[C:17]([Cl:20])(=[O:19])[CH3:18]>>[ClH:20].[C:17]([N:14]1[CH2:15][CH2:16][C:3]2[C:4](=[N:5][C:6]3[CH:7]=[CH:8][CH:9]=[CH:10][C:11]=3[C:2]=2[CH3:1])[CH2:12][CH2:13]1)(=[O:19])[CH3:18]

Participants

3

Reactant 2

HCID 6367Acetyl chlorideHCID 304399911-methyl-2,3,4,5-tetrahydro-1H-azepino[4,5-b]quinoline

Product 1

HCID 21503670HCID 21503670, compoundYield 60%

Procedure

3-Acetyl-1,2,4,5-tetrahydro-11-methyl-3H-azepino[4,5-b]quinoline hydrochloride was prepared from 1,2,4,5-tetrahydro-11-methyl-3H-azepino[4,5-b]quinoline and acetyl chloride analogous to Example 63.

Sources & evidence

ORD record
ord-fba72cf888fa415a85e27a5c62705c34
Source dataset
uspto-grants-1976_10
Patent number
US03987047

Reaction notes

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