Acetyl chloride → HCID 21503490, compound

HRID 1288145Notes

Reaction equation

HRID 1288145 reaction equation
[C:1]1([C:7]2[C:16]3[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=3[N:10]=[C:9]3[CH2:17][CH2:18][NH:19][CH2:20][CH2:21][C:8]=23)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:22]([Cl:25])(=[O:24])[CH3:23]>>[ClH:25].[C:22]([N:19]1[CH2:20][CH2:21][C:8]2[C:9](=[N:10][C:11]3[CH:12]=[CH:13][CH:14]=[CH:15][C:16]=3[C:7]=2[C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[CH2:17][CH2:18]1)(=[O:24])[CH3:23]

Participants

3

Reactant 2

HCID 6367Acetyl chlorideHCID 21503450HCID 21503450, compound

Product 1

HCID 21503490HCID 21503490, compoundYield 90%

Procedure

3-Acetyl-1,2,4,5-tetrahydro-11-phenyl-3H-azepino[4,5-b]quinoline hydrochloride was prepared from 1,2,4,5-tetrahydro-11-phenyl-3H-azepino[4,5-b]quinoline and acetyl chloride analogous to Example 63.

Sources & evidence

ORD record
ord-69fea217043f4e7bbf2349645c89eba6
Source dataset
uspto-grants-1976_10
Patent number
US03987047

Reaction notes

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