Tetrafluoro-m-phenylenediamine dihydrochloride → HCID 21503414, compound

HRID 1288157Notes

Reaction equation

HRID 1288157 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([CH2:10]N)=O)=[CH:4][CH:3]=1.[C:12]1([NH2:23])[C:17](F)=[C:16](F)[C:15](F)=[C:14]([NH2:21])[C:13]=1F.Cl.Cl>>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]2[C:8]([CH3:10])=[C:17]3[CH2:16][CH2:15][NH:21][CH2:14][CH2:13][C:12]3=[N:23][C:6]=2[CH:7]=1

Participants

3

Reactant 2

HCID 149026Tetrafluoro-m-phenylenediamine dihydrochlorideHCID 4099442-Amino-1-(4-methylphenyl)ethan-1-one

Product 1

HCID 21503414HCID 21503414, compound

Procedure

1,2,4,5-Tetrahydro-8,11-dimethyl-3H-azepino[4,5-b]quinoline, 2,3,4,5-tetrahydro-8,11-dimethyl-1H-azepino[4,5-b]quinoline and their dihydrochlorides were prepared from hexahydro-azepinone-(4) hydrochloride and 2-amino-4-methyl-acetophenone analogous to Example 127. Yield of the dihydrochloride of the [4,5-b]-isomer: 17% of theory; m.p. 290°-292° C. (decomp.).

Sources & evidence

ORD record
ord-0f4689fa441b486e8cf37d29ba3a9042
Source dataset
uspto-grants-1976_10
Patent number
US03987047

Reaction notes

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