Bromine → HCID 21503628, compound

HRID 1288159Notes

Reaction equation

HRID 1288159 reaction equation
[ClH:1].Cl.[NH2:3][C:4]1[CH:13]=[CH:12][C:11]2[N:10]=[C:9]3[CH2:14][CH2:15][CH2:16][NH:17][CH2:18][C:8]3=[C:7]([CH3:19])[C:6]=2[CH:5]=1.[Br:20]Br>>[ClH:1].[ClH:1].[NH2:3][C:4]1[CH:13]=[CH:12][C:11]2[N:10]=[C:9]3[CH2:14][CH2:15][CH2:16][NH:17][CH2:18][C:8]3=[C:7]([CH3:19])[C:6]=2[C:5]=1[Br:20]

Participants

3

Reactant 2

HCID 24408BromineHCID 21503582HCID 21503582, compound

Product 1

HCID 21503628HCID 21503628, compoundYield 60%

Procedure

9-Amino-10-bromo-2,3,4,5-tetrahydro-11-methyl-1H-azepino[4,3-b]quinoline dihydrochloride was prepared from 9-amino-2,3,4,5-tetrahydro-11-methyl-1H-azepino[4,3-b]quinoline dihydrochloride by bromination with an equimolar quantity of bromine analogous to Example 148.

Sources & evidence

ORD record
ord-72e80f21ac2641a59fb28fc764e720d8
Source dataset
uspto-grants-1976_10
Patent number
US03987047

Reaction notes

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