Bromine → HCID 21503650, compound

HRID 1288160Notes

Reaction equation

[ClH:1].Cl.[NH2:3][C:4]1[CH:13]=[CH:12][C:11]2[N:10]=[C:9]3[CH2:14][CH2:15][NH:16][CH2:17][CH2:18][C:8]3=[C:7]([CH3:19])[C:6]=2[CH:5]=1.[Br:20]Br>>[ClH:1].[ClH:1].[NH2:3][C:4]1[CH:13]=[CH:12][C:11]2[N:10]=[C:9]3[CH2:14][CH2:15][NH:16][CH2:17][CH2:18][C:8]3=[C:7]([CH3:19])[C:6]=2[C:5]=1[Br:20]

Participants

Reactant 2

HCID 24408Bromine

HCID 21503529HCID 21503529, compound

Product 1

HCID 21503650HCID 21503650, compound

Procedure

9-Amino-10-bromo-1,2,4,5-tetrahydro-11-methyl-3H-azepino[4,5-b]quinoline dihydrochloride was prepared from 9-amino-1,2,4,5-tetrahydro-11-methyl-3H-azepino[4,5-b]quinoline dihydrochloride by bromination with an equimolar quantity of bromine analogous to Example 148.

Sources & evidence

ORD record: ord-7c196572a6b0400db69c036817f51bf6
Source dataset: uspto-grants-1976_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03987047

Reaction notes

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