Chloroacetonitrile → HCID 21503626, compound

HRID 1288184Notes

Reaction equation

HRID 1288184 reaction equation
[CH3:1][C:2]1[C:11]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[N:5]=[C:4]2[CH2:12][CH2:13][NH:14][CH2:15][CH2:16][C:3]=12.[Cl:17][CH2:18][C:19]#[N:20]>>[ClH:17].[ClH:17].[CH3:1][C:2]1[C:11]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[N:5]=[C:4]2[CH2:12][CH2:13][N:14]([CH2:18][C:19]#[N:20])[CH2:15][CH2:16][C:3]=12

Participants

3

Reactant 2

HCID 7856ChloroacetonitrileHCID 304399911-methyl-2,3,4,5-tetrahydro-1H-azepino[4,5-b]quinoline

Product 1

HCID 21503626HCID 21503626, compoundYield 25%

Procedure

2-[1,2,4,5-Tetrahydro-11-methyl-3H-azepino[4,5-b]quinoline-3-yl]acetonitrile dihydrochloride was prepared from 1,2,4,5-tetrahydro-11-methyl-3H-azepino[4,5-b]quinoline and chloroacetonitrile analogous to Example 186.

Sources & evidence

ORD record
ord-e0e1acf744c74c5f8720a73ea9599892
Source dataset
uspto-grants-1976_10
Patent number
US03987047

Reaction notes

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