Sodium Iodide → HCID 21503451, compound

Participants

Reaction Steps

A mixture of 4.5 gm (15 millimols) of 3-benzyl-11-hydroxy-1,2,4,5-tetrahydro-3H-azepino[4,5-b]quinoline, 4.2 gm (30 millimols) of β-phenethyl chloride, 4.15 gm (30 millimols) of potassium carbonate, 5 gm of sodium iodide and 10 ml of butanone-(2) was boiled for 207 hours. The mixture was then suction-filtered, and the filter cake was purified by column chromatography on silicagel with ethyl acetate as the eluant. Yield: 73% of theory; m.p. <20° C.

Provenance & Evidence