Acetone → HCID 178473670, compound

HRID 1288220Notes

Reaction equation

HRID 1288220 reaction equation
[CH2:1]([O:3][C:4](Cl)=[O:5])[CH3:2].[S-:7][C:8]#[N:9].[K+].CC(C)=[O:13]>>[N-:9]=[C:8]=[S:7].[CH2:1]([O:3][C:4](=[O:5])[OH:13])[CH3:2]

Participants

4

Reactant 3

HCID 180AcetoneHCID 10928Ethyl chloroformateHCID 516872Potassium thiocyanate

Product 1

HCID 178473670HCID 178473670, compoundYield 32%

Procedure

218 g of freshly distilled chloroformic acid ethyl ester were added to 200 g (2 mols) of potassium thiocyanate in 800 ml of acetone at 60°-70° C and the mixture was stirred for 2 hours. The solids which had been separated out were then filtered off, the solvent was evaporated off and the residue was distilled at 55° C and 12 mm Hg. 84 g (32% of theory) of carbonic acid ethyl ester isothiocyanate were obtained.

Workup

  1. customThe solids which had been separated out
  2. filtrationwere then filtered off
  3. customthe solvent was evaporated off
  4. distillationthe residue was distilled at 55° C

Sources & evidence

ORD record
ord-f23897a1158a43c795c17fb77e8f4914
Source dataset
uspto-grants-1976_10
Patent number
US03987168

Reaction notes

Loading…