Sodium Dithionite → HCID 136354619, compound

HRID 1288285Notes

Reaction equation

HRID 1288285 reaction equation
[NH2:1][C:2]1[N:3]=[C:4]([CH:11]2[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]2)[NH:5][C:6](=[O:10])[C:7]=1[N:8]=O.S(S([O-])=O)([O-])=O.[Na+].[Na+]>O>[NH2:1][C:2]1[N:3]=[C:4]([CH:11]2[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]2)[NH:5][C:6](=[O:10])[C:7]=1[NH2:8]

Participants

4

Reactant 2

HCID 24489Sodium DithioniteHCID 136354620HCID 136354620, compound

Product 1

HCID 136354619HCID 136354619, compoundYield 81.1%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To water (50 ml.), stirred at 70° C, were added in alternate portions 4-amino-2-cyclohexyl-5-nitrosopyrimid-6-one (25 g.) and sodium dithionite until the blue colour was discharged. The pale yellow solid was filtered off and washed with water to give 4,5-diamino-2-cyclohexylpyrimid-6-one (19 g.), m.p. 232-238° C. (with decomposition).

Workup

  1. filtrationThe pale yellow solid was filtered off
  2. washwashed with water

Sources & evidence

ORD record
ord-8f5a8664ab8f44bd9637590d1a736c89
Source dataset
uspto-grants-1976_10
Patent number
US03987160

Reaction notes

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