反应详情

A solution of triethyloxonium borofluoride (34 g.) in anhydrous methylene chloride (90 ml.) was added during 5 minutes to a solution of crude 5-methyl-2-propoxybenzamide (34.5 g.) in anhydrous methylene chloride (300 ml.), and the solution was left to stand at room temperature overnight. The solution was concentrated to about 150 ml. and then diluted with anhydrous diethyl ether (500 ml.). The precipitated solid was filtered off and washed with anhydrous diethyl ether to give crude ethyl 5-methyl-2-propoxybenzimidate borofluoride (47 g.), m.p. 148°-150° C.

1. waitthe solution was left
2. concentrationThe solution was concentrated to about 150 ml
3. additionand then diluted with anhydrous diethyl ether (500 ml.)
4. filtrationThe precipitated solid was filtered off
5. washwashed with anhydrous diethyl ether