HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 4-Acetylamino-3,5-bis-trifluoromethylnitrobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 2,6-Bis(trifluoromethyl)-4-nitroaniline | HCID 21395879 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 4-Acetylamino-3,5-bis-trifluoromethylnitrobenzene | HCID 21482725 | — |
Reaction Steps
A mixture of 8.2 g. of 4-nitro-2,6-bis-trifluoromethylaniline, 3.6 g. acetic anhydride, and 20 ml. of pyridine is heated for 48 hours on a steam bath. The reaction mixture is poured onto ice water and the solid material is filtered, dried and recrystallized from isopropanol affording 4-acetylamino-3,5-bis-trifluoromethylnitrobenzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03987199 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-3e64137d90cc4df998af2122dc599261 |
| Source note | uspto-grants-1976_10 |