Ethyl 7-{acetyl[4-(acetyloxy)nonyl]amino}heptanoate → 7-[Acetyl(4-hydroxynonyl)amino]heptanoic acid

HRID 1288346Notes

Reaction equation

HRID 1288346 reaction equation
O1CCCCC1[O:7][CH:8]([CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])[CH2:9][CH2:10][CH2:11][N:12]([CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][C:22]([O:24]CC)=[O:23])[C:13](=[O:15])[CH3:14].C(OC(CCCCC)CCCN(CCCCCCC(OCC)=O)C(=O)C)(=O)C>>[OH:7][CH:8]([CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])[CH2:9][CH2:10][CH2:11][N:12]([CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][C:22]([OH:24])=[O:23])[C:13](=[O:15])[CH3:14]

Participants

3

Reactant 2

HCID 21503950Ethyl 7-{acetyl[4-(acetyloxy)nonyl]amino}heptanoateHCID 21503952HCID 21503952, compound

Product 1

HCID 215039297-[Acetyl(4-hydroxynonyl)amino]heptanoic acid

Procedure

The preparation of this compound is carried out essentially by the method described for Example 1, Step B except that the ethyl 7-{N-[4-(2-tetrahydropyranyloxy)-nonyl]acetamido}heptanoate of Example 1, Step B is replaced by an equimolar quantity of ethyl 7-[N-(4-acetoxynonyl)-acetamido]heptanoate; and omitting the acid treatment, there is obtained the subject compound.

Workup

  1. customThe preparation of this compound
  2. customthere is obtained the subject compound

Sources & evidence

ORD record
ord-d9e7f6ad8d624444870264d06d8190b4
Source dataset
uspto-grants-1976_10
Patent number
US03987091

Reaction notes

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