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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1288574Generated: November 2, 2026

2-Methylbenzaldehyde → HCID 12448677, compound

https://huagongshe.com/reaction/1288574

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-MethylbenzaldehydeHCID 10722—
ReactantCarbamimidoyl-acetic acid ethyl esterHCID 4599837—
SolventEthanolHCID 702—
ProductHCID 12448677HCID 1244867767%

Reaction Steps

Upon boiling a solution of 6.0 g 2-methylbenzaldehyde and 13.0 g amidinoacetic acid ethyl ester in 150 ml ethanol for 2 hours, 2,6-diamino-4-(2-methylphenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester of m.p. 158° C (ethanol) is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03988458
Source datasetuspto-grants-1976_10
ORD IDord-23569e9d02474a74bb7be12ce3df9d20
Source noteuspto-grants-1976_10