HuagongsheHuagongshe Chemistry Print Report · For research reference only
o-Fluorobenzaldehyde → HCID 12448678, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | o-Fluorobenzaldehyde | HCID 67970 | — |
| Reactant | Carbamimidoyl-acetic acid ethyl ester | HCID 4599837 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 12448678 | HCID 12448678 | 49% |
Reaction Steps
Upon boiling a solution of 6.2 g 2-fluorobenzaldehyde and 13.0 g amidinoacetic acid ethyl ester in 150 ml ethanol for 1 hour, 2,6-diamino-4-(2-fluorophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester of m.p. 128°-130° C (ethanol) is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03988458 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-964b48e51b3f40d18241508cd010ff4e |
| Source note | uspto-grants-1976_10 |