Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Carbamimidoyl-acetic acid ethyl ester → 2,6-Diamino-4-(3-carbethoxyphenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Carbamimidoyl-acetic acid ethyl ester | HCID 4599837 | — |
| 반응물 | Ethyl 3-formylbenzoate | HCID 11084437 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 2,6-Diamino-4-(3-carbethoxyphenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester | HCID 70631688 | 32% |
반응 단계
Upon boiling a solution of 8.9 g 3-carbethoxybenzaldehyde and 13.0 g amidinoacetic acid ethyl ester in 100 ml ethanol for 2 hours, 2,6-diamino-4-(3-carbethoxyphenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester of m.p. 191° C (ethanol) is obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03988458 |
| 출처 데이터셋 | uspto-grants-1976_10 |
| ORD ID | ord-4a581bcb4f5a4ceaa0984d75c3f0b856 |
| 출처 메모 | uspto-grants-1976_10 |