HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 2,5-Dimethoxythiophenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | 2,5-Dimethoxybenzenesulfonyl chloride | HCID 137025 | — |
| Catalyst | Zinc | HCID 23994 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2,5-Dimethoxythiophenol | HCID 519009 | — |
Reaction Steps
16 g of 2,5-dimethoxybenzene-sulphonyl chloride are dissolved in 100 ml of THF, while stirring, and a mixture of 20 ml of concentrated H2SO4 and 60 ml of water is then added, followed by 25 g of zinc dust, added in portions at 50°-55° and stirring is continued overnight at 20°. The THF is then stripped off and the mixture is worked up with water and methylene chloride to give 2,5-dimethoxythiophenol, b.p. 106°-108°/0.3 mm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03988468 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-c9114d044c2d44d8b78390bc4b48f57f |
| Source note | uspto-grants-1976_10 |