反应详情

Using 306 mg of p-methoxybenzyl 7-[(Z)-2-(2-tritylaminothiazol-4-yl)-2-{(S)-1-diphenylmethoxycarbonylethoxyimino}acetamido]-3-chloromethyl-3-cephem-4-carboxylate and 153 mg of 1,5-dimethyl-2-mercaptoimidazolo[4,5-c]pyridinium trifluoroacetate in place of p-methoxybenzyl 7-{(Z)-2-(2-tritylaminothiazol-4-yl)-2-methoxyiminoacetamido}-3-chloromethyl-3-cephem-4-carboxylate and 2-mercapto-4-methylthiazolo[5,4-b]pyridinium trifluoroacetate, respectively, the reaction and purification were carried out in the same manner as in Example 15(a) to obtain 334 mg of the title compound in a yield of 88%.

1. customrespectively, the reaction and purification