HCID 18925390, compound → HCID 18925422, compound

HRID 1289073Notes

Reaction equation

HRID 1289073 reaction equation
[N+:1]([C:4]1[S:5][CH:6]=[CH:7][C:8]=1[C:9]1[CH:14]=[CH:13][C:12]([CH3:15])=[CH:11][CH:10]=1)([O-])=O>O1CCOCC1>[NH2:1][C:4]1[S:5][CH:6]=[CH:7][C:8]=1[C:9]1[CH:14]=[CH:13][C:12]([CH3:15])=[CH:11][CH:10]=1

Participants

3

Reactant 1

HCID 18925390HCID 18925390, compound

Product 1

HCID 18925422HCID 18925422, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

After dissolving 0.5 g of 2-nitro-3-(4-tolyl)thiophene in 20 ml of dioxane, 0.25 g of 5% pd/C was added and catalytic reduction was carried out at room temperature for 5 hours. The solution obtained was filtered to recover the catalyst and the filtrate was used as intact for the next reaction.

Workup

  1. additionpd/C was added
  2. customThe solution obtained
  3. filtrationwas filtered
  4. customto recover the catalyst
  5. customintact for the next reaction

Sources & evidence

ORD record
ord-1fc4e35b550e4629abd579148e21a0d9
Source dataset
uspto-grants-1998_05
Patent number
US05747518

Reaction notes

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