4-Cyanobenzoyl chloride → HCID 10445222, compound

HRID 1289099Notes

Reaction equation

HRID 1289099 reaction equation
Br.[CH3:2][C@@:3]1([C:8]([OH:10])=[O:9])[CH2:7][CH2:6][CH2:5][NH:4]1.[C:11]([C:13]1[CH:21]=[CH:20][C:16]([C:17](Cl)=[O:18])=[CH:15][CH:14]=1)#[N:12]>>[C:11]([C:13]1[CH:21]=[CH:20][C:16]([C:17]([N:4]2[CH2:5][CH2:6][CH2:7][C@@:3]2([CH3:2])[C:8]([OH:10])=[O:9])=[O:18])=[CH:15][CH:14]=1)#[N:12]

Participants

3

Reactant 2

HCID 801724-Cyanobenzoyl chlorideHCID 698463122-Methyl-L-proline--hydrogen bromide (1/1)

Product 1

HCID 10445222HCID 10445222, compound

Procedure

By reacting 2-methyl-L-proline hydrobromide with p-cyanobenzoyl chloride analogously to Example 2b) there is obtained 1-(p-cyanobenzoyl)-2-methyl-L-proline. MS (EI): 213 (M-COOH)+.

Sources & evidence

ORD record
ord-9335144127b941dcadb84edf3cf2e9d1
Source dataset
uspto-grants-1998_05
Patent number
US05747522

Reaction notes

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