HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → [5-(5-thiophen-2-ylthiophen-2-yl)thiophen-2-yl]methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | (2,2':5',2''-Terthiophene)-5-carboxaldehyde | HCID 454742 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | [5-(5-thiophen-2-ylthiophen-2-yl)thiophen-2-yl]methanol | HCID 454740 | 97% |
Reaction Steps
0.5 g of 5-formyl-2,2':5',2"-terthiophene was dissolved in 20 ml of THF and stirred at room temperature, followed by adding 0.034 g of NaBH4 and stirred for 2 hours. After the reduction was completed, 50 ml of water was added. The solution was then extracted with chloroform, dried over anhydrous Na2SO4, filtered and condensed. The yellowish powder was thus obtained and the melting point thereof was 151°-152° C. (yield was 97%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05747525 |
| Source dataset | uspto-grants-1998_05 |
| ORD ID | ord-01be9ea264c4438c8b99ffec4c119299 |
| Source note | uspto-grants-1998_05 |