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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1289129Generated: October 30, 2026

Water → [5-(5-thiophen-2-ylthiophen-2-yl)thiophen-2-yl]methanol

https://huagongshe.com/reaction/1289129

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
Reactant(2,2':5',2''-Terthiophene)-5-carboxaldehydeHCID 454742—
ReactantSodium borohydrideHCID 4311764—
SolventTetrahydrofuranHCID 8028—
Product[5-(5-thiophen-2-ylthiophen-2-yl)thiophen-2-yl]methanolHCID 45474097%

Reaction Steps

0.5 g of 5-formyl-2,2':5',2"-terthiophene was dissolved in 20 ml of THF and stirred at room temperature, followed by adding 0.034 g of NaBH4 and stirred for 2 hours. After the reduction was completed, 50 ml of water was added. The solution was then extracted with chloroform, dried over anhydrous Na2SO4, filtered and condensed. The yellowish powder was thus obtained and the melting point thereof was 151°-152° C. (yield was 97%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05747525
Source datasetuspto-grants-1998_05
ORD IDord-01be9ea264c4438c8b99ffec4c119299
Source noteuspto-grants-1998_05