Sodium Acetate → HCID 73753161, compound

HRID 1289154Notes

Reaction equation

HRID 1289154 reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][C:7]([CH2:10][O:11][C:12]2[CH:19]=[CH:18][C:15]([CH:16]=O)=[CH:14][CH:13]=2)=[C:6]([CH2:20][CH2:21][CH3:22])[C:5]=1[O:23][CH3:24])(=[O:3])[CH3:2].C([O-])(=O)C.[Na+].[S:30]1[CH2:36][C:34](=[O:35])[NH:33][C:31]1=[S:32]>C(O)(=O)C>[C:1]([C:4]1[CH:9]=[CH:8][C:7]([CH2:10][O:11][C:12]2[CH:19]=[CH:18][C:15]([CH:16]=[C:36]3[S:30][C:31](=[S:32])[NH:33][C:34]3=[O:35])=[CH:14][CH:13]=2)=[C:6]([CH2:20][CH2:21][CH3:22])[C:5]=1[O:23][CH3:24])(=[O:3])[CH3:2]

Participants

5

Reactant 3

HCID 517045Sodium AcetateHCID 1201546RhodanineHCID 21191265HCID 21191265, compound

Product 1

HCID 73753161HCID 73753161, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Under nitrogen atmosphere in a round bottom flask 4-[(4-acetyl-3-methoxy-2-propylphenyl)methoxy]benzaldehyde (0.33 g, 1.01 mmol) was dissolved in 5 ml of acetic acid with stirring. To this solution was added sodium acetate (0.29 g, 3.53 mmol) followed by the addition of rhodanine (0.13 g, 0.98 mmol). The reaction mixture was heated to reflux. The progress of the reaction was monitored by thin layer chromatography. The reaction was allowed to reflux overnight.

Workup

  1. temperatureThe reaction mixture was heated to reflux
  2. temperatureto reflux overnight

Sources & evidence

ORD record
ord-33af59f872a94ac4a393b0f410f8f150
Source dataset
uspto-grants-1998_05
Patent number
US05747517

Reaction notes

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