Sodium Acetate → HCID 73753155, compound

HRID 1289157Notes

Reaction equation

HRID 1289157 reaction equation
[C:1]([C:4]1[CH:19]=[CH:18][C:7]([O:8][CH2:9][C:10]2[CH:17]=[CH:16][C:13]([CH:14]=O)=[CH:12][CH:11]=2)=[C:6]([CH2:20][CH2:21][CH3:22])[C:5]=1[O:23][C:24](=[O:26])[CH3:25])(=[O:3])[CH3:2].C([O-])(=O)C.[Na+].[S:32]1[CH2:38][C:36](=[O:37])[NH:35][C:33]1=[S:34]>C(O)(=O)C>[C:1]([C:4]1[CH:19]=[CH:18][C:7]([O:8][CH2:9][C:10]2[CH:17]=[CH:16][C:13]([CH:14]=[C:38]3[S:32][C:33](=[S:34])[NH:35][C:36]3=[O:37])=[CH:12][CH:11]=2)=[C:6]([CH2:20][CH2:21][CH3:22])[C:5]=1[O:23][C:24](=[O:26])[CH3:25])(=[O:3])[CH3:2]

Participants

5

Reactant 3

HCID 517045Sodium AcetateHCID 1201546RhodanineHCID 21191227HCID 21191227, compound

Product 1

HCID 73753155HCID 73753155, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Under a nitrogen atmosphere in a round bottom flask 4-[(4-acetyl-3-acetoxy-2-propylphenoxy)methyl]benzaldehyde (70 mg, 0.20 mmol) was dissolved in acetic acid (1 ml). To this solution was added sodium acetate (59 mg, 0.72 mmol) and then rhodanine (27.5 mg, 0.21 mmol). The reaction mixture was then heated to reflux and the progress of the reaction was monitored by thin layer chromatography.

Workup

  1. temperatureThe reaction mixture was then heated
  2. temperatureto reflux

Sources & evidence

ORD record
ord-9a7e73403d0644aa872edad0f66445e7
Source dataset
uspto-grants-1998_05
Patent number
US05747517

Reaction notes

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