Sodium Acetate → HCID 73568328, compound

HRID 1289160Notes

Reaction equation

HRID 1289160 reaction equation
[C:1]([C:5]1[CH:20]=[CH:19][C:8]([CH2:9][O:10][C:11]2[CH:18]=[CH:17][C:14]([CH:15]=O)=[CH:13][CH:12]=2)=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[S:21]1[CH2:27][C:25](=[O:26])[NH:24][C:22]1=[S:23].C([O-])(=O)C.[Na+]>C(O)(=O)C>[C:1]([C:5]1[CH:20]=[CH:19][C:8]([CH2:9][O:10][C:11]2[CH:18]=[CH:17][C:14]([CH:15]=[C:27]3[S:21][C:22](=[S:23])[NH:24][C:25]3=[O:26])=[CH:13][CH:12]=2)=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2]

Participants

5

Reactant 3

HCID 517045Sodium AcetateHCID 1201546RhodanineHCID 23411144HCID 23411144, compound

Product 1

HCID 73568328HCID 73568328, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

The 4-[(4-t-butyl)benzyloxy]benzaldehyde (2.6 g, 9 mmol) was then coupled with rhodanine (1.4 g, 10.5 mmol) by adding the reactants to sodium acetate (2.9 g, 36 mmol) and acetic acid. The reaction mixture was then heated to reflux and refluxed overnight.

Workup

  1. temperatureThe reaction mixture was then heated
  2. temperatureto reflux
  3. temperaturerefluxed overnight

Sources & evidence

ORD record
ord-1dea902e3077406aa96872609315976d
Source dataset
uspto-grants-1998_05
Patent number
US05747517

Reaction notes

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