Sodium Acetate → HCID 2885488, compound

HRID 1289162Notes

Reaction equation

HRID 1289162 reaction equation
[C:1]1([CH2:11][O:12][C:13]2[CH:20]=[CH:19][C:16]([CH:17]=O)=[CH:15][CH:14]=2)[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.C([O-])(=O)C.[Na+].[S:26]1[CH2:32][C:30](=[O:31])[NH:29][C:27]1=[S:28]>C(O)(=O)C>[C:1]1([CH2:11][O:12][C:13]2[CH:20]=[CH:19][C:16]([CH:17]=[C:32]3[S:26][C:27](=[S:28])[NH:29][C:30]3=[O:31])=[CH:15][CH:14]=2)[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 517045Sodium AcetateHCID 881941HCID 881941, compoundHCID 1201546Rhodanine

Product 1

HCID 2885488HCID 2885488, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Under a nitrogen atmosphere in a round bottom flask 4-[(naphth-1-yl)methoxy]benzaldehyde (5.25 g, 20 mmol) was dissolved in 100 ml of acetic acid. To this solution was added sodium acetate (5.74 g, 70 mmol) and rhodanine (2.66 g, 20 mmol). The reaction mixture was raised to the reflux temperature and maintained at this temperature. The progress of the reaction was monitored by thin layer chomratography.

Workup

  1. temperatureThe reaction mixture was raised to the reflux temperature
  2. temperaturemaintained at this temperature

Sources & evidence

ORD record
ord-380aa42e8c924d818df1a6ad5180441f
Source dataset
uspto-grants-1998_05
Patent number
US05747517

Reaction notes

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