Rhodanine → HCID 73753156, compound

HRID 1289166Notes

Reaction equation

HRID 1289166 reaction equation
[C:1]([C:9]1[CH:24]=[CH:23][C:12]([CH2:13][O:14][C:15]2[CH:22]=[CH:21][C:18]([CH:19]=O)=[CH:17][CH:16]=2)=[CH:11][CH:10]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[S:25]1[CH2:31][C:29](=[O:30])[NH:28][C:26]1=[S:27]>>[C:2]1([C:1]([C:9]2[CH:24]=[CH:23][C:12]([CH2:13][O:14][C:15]3[CH:22]=[CH:21][C:18]([CH:19]=[C:31]4[S:25][C:26](=[S:27])[NH:28][C:29]4=[O:30])=[CH:17][CH:16]=3)=[CH:11][CH:10]=2)=[O:8])[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 1201546RhodanineHCID 153182414-[(4-Benzoylphenyl)methoxy]benzaldehyde

Product 1

HCID 73753156HCID 73753156, compound

Procedure

The 4-(4-benzoylbenzyloxy)benzaldehyde was coupled with rhodanine to yield the title compound by admixing the 4-(4-benzoylbenzyloxy)benzaldehyde (2.09 g, 6.3 mmol) with rhodanine (1.0 g, 7.5 mmol), sodium acetate (1.8 g, 22 mmol) and acetic acid (75 ml) in a 250 ml flask. The reaction mixture was heated to reflux and refluxed overnight.

Sources & evidence

ORD record
ord-c3ed104fba124cafa34927afd44f5ea3
Source dataset
uspto-grants-1998_05
Patent number
US05747517

Reaction notes

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