HCID 54099788, compound → HCID 18795085, compound

HRID 1289194Notes

Reaction equation

HRID 1289194 reaction equation
[CH2:1]([C:4]1[CH:9]=[CH:8][C:7]([CH:10]=[CH:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]([OH:19])=[O:18])=[CH:6][CH:5]=1)[CH2:2][CH3:3]>[Pd].[O-]S([O-])(=O)=O.[Ba+2]>[CH2:1]([C:4]1[CH:9]=[CH:8][C:7]([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]([OH:19])=[O:18])=[CH:6][CH:5]=1)[CH2:2][CH3:3]

Participants

3

Reactant 1

HCID 54099788HCID 54099788, compound

Product 1

HCID 18795085HCID 18795085, compoundYield 95.3%

Reagents, catalysts & solvents 1

HCID 16218511Pd barium sulfateCatalyst

Procedure

This compound was synthesized from 8-(p-propylphenyl)-7-octenoic acid (1.30 g, 5 mmol) and Pd/BaSO4 (130 mg) by a hydrogenation reaction. Crystallization (petroleum ether) afforded the product (1.25 g, 95%) as white crystals (mp 42°-43° C.). IR: 3400-2500, 1705 cm-1 ; 1H-NMR: 0.95 (t, 3H), 1.45 (m, 12H), 2.50 (m, 6H), 7.05 (s, 4H), 11.40 (bs, 1H). Anal. Calcd. for C17H26O2 : C, 77.82, H, 9.99%; Found: C, 77.75, H, 10.04%.

Workup

  1. customCrystallization (petroleum ether)

Sources & evidence

ORD record
ord-18aaecedaf9341bb878151d727d80565
Source dataset
uspto-grants-1998_05
Patent number
US05747537

Reaction notes

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