HuagongsheHuagongshe Chemistry Print Report · For research reference only
O-Cresol → Acetic acid, 2-methylphenyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | O-Cresol | HCID 335 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | Acetic acid, 2-methylphenyl ester | HCID 10778 | — |
Reaction Steps
Ice (300 g) was added to o-cresol (21.6 g, 0.2 mol) dissolved in a solution of sodium hydroxide (12 g, 0.3 mol in water (100 ml). Acetic anhydride (30.6 g, 0.3 mol) was then added and the mixture was shaken for 1 min. The product was extracted into ether and then purified by reduced pressure distillation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05750050 |
| Source dataset | uspto-grants-1998_05 |
| ORD ID | ord-9fe5a1ed35804d78bb267478794bd29d |
| Source note | uspto-grants-1998_05 |