Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trimethylsilyl iodide → 4-(Bromomethyl)cyclohexan-1-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trimethylsilyl iodide | HCID 85247 | — |
| 반응물 | 1-(Bromomethyl)-4-methoxycyclohexane | HCID 21706529 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 4-(Bromomethyl)cyclohexan-1-ol | HCID 21832707 | — |
반응 단계
The 4-methoxycyclohexylbromomethane compound (C-4) (2.6 g) in chloroform (7.8 g) was cooled with ice. Then trimethylsilyliodide (2.2 ml) was transferred to the C-4 solution. It was stirred at ambient temperature for 8 h, and then quenched with methanol. Then, volatiles were removed to obtain the desired alcohol in almost quantitative yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05750300 |
| 출처 데이터셋 | uspto-grants-1998_05 |
| ORD ID | ord-7df562be99754e0aaf4e0a7c5c27f733 |
| 출처 메모 | uspto-grants-1998_05 |