HCID 67639801, compound → HCID 18920851, compound

Participants

Reaction Steps

First, 3.3 g of 2,3-difluoro-4'-[8,8-bis(6-benzyloxyhexyl)-6-octene-1-yl]oxybiphenyl, 1 g of 10% Pd-C, and 100 ml of tetrahydrofuran were placed in a 200 ml autoclave. The mixture was stirred at room temperature for 2 days under a hydrogen pressure of 10 kg/cm2. A catalyst was filtered away and a filtrate was concentrated. Thereafter, the residue was purified by silica gel column chromatography (eluent: toluene/ethyl acetate=3/2) to obtain 2.3 g of 2,3-difluoro-4'-[8,8-bis(6-hydroxyhexyl)octyl]oxybiphenyl (Y: 93.6%). The compound thus obtained had a purity of 98.8% by HPLC.

Provenance & Evidence