Benzyl 2-(triphenyl-lambda5-phosphanylidene)acetate → Phenylmethyl 4-(2,3-dihydro-1H-inden-2-yl)-2-butenoate

Participants

Reaction Steps

Dissolved in 50 ml of methylene chloride were 3.97 g (24.8 mmol) of (indan-2-yl)acetaldehyde, and 12.2 g (29.8 mmol) of benzyloxycarbonylmethylene triphenylphosphorane were added to the solution, followed by stirring for 1.5 hours. After the solvent was distilled off, the residue was purified by column chromatography on silica gel (ethyl acetate:hexane=1:20) to obtain 6.45 g of a colorless oily substance. Yield: 89%.

Provenance & Evidence