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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1289502Generated: November 1, 2026

4-Fluoro-2-methylaniline → HCID 18921679, compound

https://huagongshe.com/reaction/1289502

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-2-methylanilineHCID 67982—
ReactantHCID 18921765HCID 18921765—
SolventDimethylformamideHCID 6228—
ProductHCID 18921679HCID 1892167964.2%

Reaction Steps

After 2-methyl-4-fluoroaniline(0.77 ml, 6.93 mmol) was added to a mixture solution of 6-ethyl-4-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)-2-chloropyrimidine(1.0 g, 3.47 mmol) and dimethylformamide(5 ml), 0.92 g of the titled compound was obtained in accordance with the same procedure as in Step 2 of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05750531
Source datasetuspto-grants-1998_05
ORD IDord-718f89c391494c7c9ab16e60f3db637d
Source noteuspto-grants-1998_05