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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1289505Generated: November 2, 2026

O-Toluidine → HCID 18921661, compound

https://huagongshe.com/reaction/1289505

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
ReactantHCID 18921765HCID 18921765—
SolventDimethylformamideHCID 6228—
ProductHCID 18921661HCID 1892166162.1%

Reaction Steps

After 2-methylaniline(0.46 ml, 4.31 mmol) was added to a mixture solution of 6-ethyl-4-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)-2-chloropyrimidine(0.61 g, 2.12 mmol) and dimethylformamide(5 ml), 0.52 g of the titled compound was obtained in accordance with the same procedure as in Step 2 of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05750531
Source datasetuspto-grants-1998_05
ORD IDord-4086e533c5504056b6a2c5e1c9dd1b80
Source noteuspto-grants-1998_05